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促分裂原活化蛋白激酶激酶3 (phospho Ser218)多克隆抗體

貨號 品牌 CAS 規(guī)格 銷售價(RMB) 折扣價(RMB) 備注 數量
ABP50358-100 μL Abbkine 100μL 1616 1616
ABP50358-30μL Abbkine 30μL 739 739
ABP50358-100μL Abbkine 100μL 1616 1616
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商品信息

產品英文名稱MEK-3 (phospho Ser218) Polyclonal Antibody
免疫原合成多肽:人源蛋白MEK-3,磷酸化多肽,中心氨基酸為S189.
宿主
反應性人, 大鼠, 小鼠
應用ELISA, IHC-P, WB
實驗建議最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為:WB:1:500-1:2000,IHC-p:1:100-1:300,ELISA:1:5000。 尚未在其他應用中測試。
克隆性多克隆
純化工藝使用表位特異性的免疫原,通過親和層析,從兔抗血清中親和純化抗體。

商品屬性

產品形式液體溶液
濃度1 mg/ml
儲存緩沖液含有50%甘油,0.5%BSA和0.02%疊氮化鈉的PBS緩沖液。
保存建議自發(fā)貨之日起,-20°C可穩(wěn)定保存1年。為最大限度的避免損失,請在打開管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復凍融。
運輸條件藍冰運輸
警告本文列出的產品僅供研究使用,不適用于人類或臨床診斷。我們產品所推薦應用,不是建議使用我們的產品去違反任何專利或許可證。對于使用本產品可能發(fā)生的專利侵權或其他違規(guī)行為,我們不承擔任何責任。

附加信息

背景Mitogen-activated protein kinase 3 encoded by MAP2K3 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. Mitogen-activated protein kinase 3 is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. Mitogen-activated protein kinase 3 can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of Mitogen-activated protein kinase 3 is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for MAP2K3.
基因ID5606
別名MAP2K3; MEK3; MKK3; PRKMK3; SKK2; Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPKK 3; MAPK/ERK kinase 3; MEK 3; Stress-activated protein kinase kinase 2; SAPK kinase 2; SAPKK-2; SAPKK2
其它該抗體可檢測內源蛋白
蛋白質IDP46734